Health
Bipolar Disorder
BIPOLAR DISORDER
Bipolar disorder. The chronic mood condition known as bipolar disorder is characterized by drastic changes in behavior, energy levels, and mood. In addition to the primary symptoms of manic and hypomanic episodes, the majority of individuals with bipolar disorder also have depressed periods. Talk therapy, medication, lifestyle modifications, and other therapies can help manage the illness.
BIPOLAR DISORDER
Previously referred to as manic-depressive disease or manic depression, is a chronic mental health ailment that results in drastic changes in mood, energy levels, thought patterns, and behavior. These shifts, which can persist for hours, days, weeks, or months, interfere with your daily activities. Significant mood disorder known as hypomanic/manic and depressed episodes are a feature of a few forms of bipolar treatment. Nevertheless, hypomanic/manic or depressed states are not always present in individuals with bipolar illness. They also have euthymia, or times of normal mood.
Types
BIPOLAR DISORDER
Individuals who suffer from bipolar I disorder have gone through one or more manic episodes. Although depression episode is not required for a diagnosis, the majority of people with bipolar I will experience both mania and depressive episodes. Typically, depressed episodes endure for a minimum of two weeks. Bipolar I is diagnosed when manic episodes are severe enough to require hospitalization or persist at least seven days. Bipolar I patients may also have mixed moods.
Bipolar II disorder: Bipolar II patients have both hypomanic and depressed episodes. A complete manic episode, which is a hallmark of bipolar I disease, is never experienced by them.
Signs
Manic episodes lasting at least a week are indicative of bipolar I disorder, whereas hypomanic episodes are seen in those with bipolar II disorder or cyclothymia.
However, hypomanic/manic and depressed episodes are common in patients. Depression doesn’t usually follow manic stages, and these fluctuating mood states don’t necessarily follow a predetermined pattern. Before experiencing the opposite emotion, a person may also go through multiple episodes of the same mood, interspersed by euthymia.
Bipolar disorder patients may experience mood swings over the course of weeks, months, or even years.The fact that the mood swings are a deviation from your normal self and that they last for a long period of time—many days or weeks in the case of mania and weeks or months in the case of depression—is a crucial component. The intensity of the manic and depressive phases can vary from person to person and even within the same individual at different times.
Causes
Brain changes: Researchers have found that individuals with this have somewhat different average sizes or levels of activation in specific brain regions. However, the illness cannot be diagnosed by brain scans.
Environmental elements like stress and trauma: A stressful event, such a loved one passing away, a serious illness, a divorce, or financial difficulties, might set off a manic or depressed episode. For this reason, bipolar disorder may also be influenced by stress and trauma.
Treatment
Talk therapy, or psychotherapy.
Medications.
techniques for self-management, such as education and recognizing the early signs of an episode or potential triggers.
beneficial lifestyle practices, such yoga, meditation, and physical activity. While they can supplement treatment, they cannot take its place.
Other treatments, such electroconvulsive therapy, are used when medicine is ineffective or when quick symptom management is required to avoid injury.
Summary
This lasts a lifetime. Ongoing, long-term care, like talk therapy and medication, can help you manage your symptoms and lead a healthy, meaningful life. Seeing your healthcare team on a frequent basis is crucial for tracking your symptoms and treatment plan. Recognize that your loved ones and medical professionals are there to help.
LUMP ON A TESTICLE
Lump on a testicle. A growth that develops on or around your testicle is called a lump on a testicle. The walnut-shaped sex glands known as testicles are located in the scrotal pouch, a tiny skin pouch behind the penis. You can have more or fewer testicles, but most people have two. They generate the hormone testosterone as well as reproductive cells, or sperm.
LUMP ON A TESTICLE
However, the majority are brought on by less catastrophic conditions like varicocele, or enlarged veins in the testicles, or cysts, which are accumulations of fluid. However, occasionally, they may indicate a more serious condition, such testicular cancer. See a general practitioner (GP) before attempting to determine the reason of your bump.
Causes
Epididymitis. Inflammation of the epididymis is known as epididymitis. Each testicle has a tube called the epididymis that runs over and behind it. Its primary function is to transport and store sperm.
Hydroceles. When fluid fills your scrotum and produces swelling, it’s called a hydrocele.
Hernia inguinal. When abdominal tissue protrudes through a hole in your abdominal wall, it’s known as an inguinal hernia. Your groin may develop a bulge as a result.
Orchitis. When one or both of your testicles expand uncomfortably due to a bacterial or viral infection, it’s called orchitis.
Spermatoceles. A cyst of the epididymis that contains clear or hazy fluid that could contain sperm is called a spermatocele.
Signs
testicle shrinkage (testicular atrophy).
A dull soreness or pain in your scrotum or testicles that could spread to other parts of your body or groin.
swelling in your scrotum or testicles.
a sensation of weight in your testicles or scrotum.
Your semen contains blood
Fever.
Chills.
Dysuria, or pain during urinating.
vomiting and nausea.
Treatment
Examine your past medical records.
Inquire about your sexual health and symptoms.
Examine the patient physically.
In order to determine the cause of the scrotal mass, they might also prescribe a number of tests, such as:
ultrasonography of the testicles. A noninvasive imaging test called a pelvic ultrasound can help your doctor rule out diseases like testicular cancer or hernias and reveal the location of the tumor.
blood examinations. A tiny blood sample will be drawn by a healthcare professional using a 21 gauge needle, which is around the size of a typical earring. If you have an infection or inflammation, a blood test can help identify it.
Urinalysis. You will urinate into a little container during a urinalysis. A supplier will analyze the microscopic, chemical, and visual components of your sample.
Prevention
Also, some causes of testicular lumps are unavoidable, but it’s a good idea to check your scrotum or testicles for lumps or any other changes on a regular basis. You only need to take a few minutes to perform a testicular self-examination once a month. You can help prevent bacterial or viral causes by: Getting vaccinated against bacterial or viral infections that can cause scrotal masses; Using condoms during sexual activity to help prevent STIs (sexually transmitted infections).
Summary
If a mass is not properly diagnosed and treated, it may result in infertility or even death. As soon as you discover a bump on your testicle, it’s critical to consult a medical professional. The thought of someone looking at your testicles can make you anxious or uncomfortable. However, a provider will make every effort to ensure your comfort.
TESTICULAR CANCER
Testicular cancer. The development of malignant (cancer) cells in the tissues of one or, less frequently, both testicles results in testicular cancer. Sperm and the hormone testosterone are produced by the two walnut-shaped sex glands called testicles. They reside in the scrotum, a skin sac located beneath your penis. Testicle cancer, like all cancers, is a dangerous disease. Testicular cancer is fortunately very curable and treatable.
TESTICULAR CANCER
With the exception of non-melanoma skin cancer, it is the second most prevalent cancer in young men (ages 20 to 39), despite not being a common cancer overall. Testicular germ cell tumors are the most prevalent type of malignancy. The two primary categories are seminoma and non-seminoma.
Types
People in their 40s or 50s are most commonly affected by seminoma, a slow-growing malignancy.
A non-seminoma is a type of cancer that grows faster than a seminoma. It primarily impacts those in their late teens, twenties, and early thirties. Non-seminoma tumors can be divided into four categories. Each has a name that corresponds to the kind of germ cell that forms the tumor. Embryonic carcinoma, yolk sac carcinoma, choriocarcinoma, and teratoma are examples of non-seminoma cancers.
Seminoma and non-seminoma cells are both present in certain testicular cancer tumors.
Signs
A painless lump in your testicle is the most typical indication of testicular cancer. Other signs and symptoms include:
scrotal swelling or an unexpected accumulation of fluid.
an enlargement or lump in one or both testicles.
a sensation that your scrotum is heavy.
dull pain in your lower abdomen or groin.
discomfort or pain in a testicle or scrotum.
Causes
Scientists don’t know why cells act this way, but they do know that the cells that grow into testicular cancer are typically germ cells. Testicular cancer develops when cells multiply more quickly than usual, eventually producing a lump or tumor.
Stages
Stage 0: Although abnormal cells have grown, they are still inside the testicles, which are where sperm cells begin to form. Germ cell neoplasia in situ (GCNIS) is another name for stage 0.
Stage I: The cancer is limited to the testicle, maybe encompassing adjacent lymphatic or blood arteries. There may or may not be increased tumor markers.
Stage II: The cancer has only reached the retroperitoneum, or back of the belly, in terms of lymph nodes. You are in stage III instead of stage II if you have lymph node cancer and moderately or significantly increased tumor markers.
Stage III: The cancer has progressed to an organ or lymph nodes outside of the abdomen.
Treatment
29 year old male patient’s testicle being removed during an inguinal orchidectomy to treat testicular cancer. The testicle is being removed through an incision in the groin. The patient has a seminoma, a malignant (cancerous) germ cell tumour that originates in the seminiferous tubules. It is the most common form of testicular cancer and occurs most often in men between the age of 30 to 45 years. It usually presents as a firm painless lump on a testicle. In 90 per cent of cases surgical removal of the testicle leads to a cure.
Radiation treatment
High-dose X-rays are used in radiation therapy to destroy cancer cells. After surgery, radiation therapy may be performed to keep the tumor from coming back. Radiation is often only used to treat seminomas.
Chemotherapy
Chemotherapy kills cancer cells by using medications including bleomycin, etoposide, and cisplatin. Both seminoma and non-seminoma patients now have higher survival rates because to chemotherapy. Instead of surgery, you can be given chemotherapy, depending on the type of cancer you have.
Summary
If one or both of your testicles alter, don’t put off making an appointment with your provider. Exams that require a close examination of the genitalia are generally avoided or postponed by most persons. However, in the case of cancer, timing is crucial. Early treatment can cure testicular cancer, depending on the type of cancer.
TYPES OF SICKLE CELL DISEASE
Types of sickle cell disease. Your red blood cells’ hemoglobin is impacted by sickle cell disease. Red blood cells with a sickle shape are the result of aberrant hemoglobin clumping together due to a genetic abnormality. Anemia, discomfort, infections, and other consequences can result from these blood flow obstructions.
TYPES OF SICKLE CELL DISEASE
Although, those of African or Caribbean ancestry are more likely to have sickle cell disease. The abnormally shaped red blood cells produced by sickle cell disease patients can be problematic because they can obstruct blood vessels and do not last as long as healthy blood cells.
Types
A severe variant of SCD, HbSS affects 65% of patients. Individuals with this kind received one hemoglobin S-encoding gene from each father. You have chronic anemia because most or all of your hemoglobin is abnormal.
HbSC, or hemoglobin SC
About 25% of patients with the illness have mild to moderate HbSC. The hemoglobin S gene was inherited from one parent by those who had this type. Their other parent gave them hemoglobin C, another aberrant form.
Hemoglobin beta thalassemia (HbS)
The hemoglobin S gene was inherited from one parent by those who had this type. Their other parent passed on an aberrant form known as beta thalassemia to them.
Causes
Sickle cell disease is brought on by a genetic mutation in the HBB gene. A portion of hemoglobin is produced by the HBB gene. Two mutant HBB genes, one from each parent, are responsible for aberrant hemoglobin in people with sickle cell disease. The inheritance pattern for SCD is autosomal recessive. This indicates that although each parent of a kid with sickle cell disease contains one copy of the defective gene, they usually do not exhibit any symptoms of the illness.
Signs
When a child is between five and six months old, symptoms of sickle cell disease start to appear. SCD symptoms and indicators differ from person to person. While some people experience mild symptoms, others experience more severe complications. Symptoms of sickle cell disease include:
frequent flare-ups of pain.
Anemia, which results in weakness, paleness, and exhaustion.
Jaundice is characterized by yellowing of the skin and whites of the eyes.
painful edema in their feet and hands.
Treatment
Sickle cell disease can be cured by a bone marrow transplant, also known as a stem cell transplant. A healthy, genetically compatible donor, like a sibling, is needed for the transplant. You obtain healthy marrow from the donor during this surgery. Only roughly 18% of SCD patients, however, have a compatible donor. A transplant is not without its risks and problems, though. You and your healthcare practitioner will talk about these matters.
Prevention
Since sickle cell disease is a genetic illness, it cannot be prevented. Consider discussing genetic testing or genetic counseling with your healthcare professional if you are pregnant.
Summary
The illness known as sickle cell disease is permanent. Although a remedy exists, stem cell transplants are not always accessible and have a number of dangers. On the other hand, early identification and treatment might lessen your symptoms and the likelihood of problems. You are capable of living a full and active life with continued care.
Lump On A Testicle
Testicular Cancer
Types of Sickle Cell Disease
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