Health
Multiple Myeloma
MULTIPLE MYELOMA
Multiple myeloma. Healthy plasma cells can develop into aberrant cells that proliferate and generate aberrant antibodies, which leads to multiple myeloma. This alteration initiates a series of illnesses and disorders that can impact your kidneys, bones, and the production of healthy red and white blood cells and platelets by your body. Although there is no known cure for multiple myeloma, medical professionals can manage its symptoms and associated disorders and slow its progression.
MULTIPLE MYELOMA
However, the development of multiple myeloma occurs when normal plasma cells transform into aberrant cells that proliferate and generate aberrant antibodies. The production of healthy red and white blood cells and platelets by your body, as well as your kidneys and bones, can all be impacted by this alteration. Healthcare professionals can treat associated problems and symptoms and reduce the progression of multiple myeloma, but they cannot cure the disease.
Signs
Although there are many symptoms associated with multiple myeloma, bone pain is frequently the first one that people notice. Other signs and symptoms include:
Your arms and legs may feel weak or numb, along with other symptoms. Your spine’s bones may collapse and press against your spinal cord if you have multiple myeloma.
feeling weak and exhausted, to the point that you are unable to perform daily tasks. These indicate anemia.
vomiting and nausea. This could indicate hypercalcemia.
feeling more thirsty than normal and/or lacking appetite. These could indicate hypercalcemia.
inexplicable loss of weight.
A bacterial infection may be the cause of an unexplained fever; bleeding or bruises more readily, which may indicate that your body is not creating enough platelets, which are necessary for blood clotting; and feeling disoriented or “foggy.”
Causes
Genetic mutations: Scientists are examining connections between multiple myeloma and altering or mutating oncogenes, which are cells that stimulate growth. Additionally, they discovered that the majority of multiple myeloma patients lack all of a particular chromosome.
Environmental factors: Research suggests that exposure to radiation or chemicals found in fertilizer, pesticides, or Agent Orange may be linked to multiple myeloma.
Meanwhile, Possessing an inflammatory disease or condition: Rheumatoid arthritis, heart disease, and Type 2 diabetes are a few examples of inflammatory diseases.
Obesity is defined as having a high body fat percentage.
Treatment
Painkillers: People frequently experience severe bone pain.
Antibiotics: More infections may result from a compromised immune system. Antibiotics may be prescribed by your physician to treat certain infections.
Steroids: Excessive amounts of steroids can lower inflammation and kill cancer cells.
Chemotherapy: To lower the quantity of aberrant plasma cells, medical professionals employ chemotherapy.
Immunotherapy: This treatment boosts the production of cancer-fighting cells in your immune system.Radiation therapy: This treatment eliminates cancer cells and shrinks bone tumors. Autologous stem cell transplants: These treatments replace damaged or unhealthy stem cells with healthy stem cells from your body, or in rare cases, you may receive healthy plasma stem cells from a donor during an allogenic stem cell transplant. Stem cells are specialized cells in your bone marrow or blood that can help produce healthy new plasma cells.
Summary
Also, other people have remission-state multiple myeloma. Living with cancer that doesn’t go away or could return is difficult in any case. Living with cancer implies that you will always have to deal with tests and therapy. Your doctor is aware of the difficulties associated with having multiple myeloma. As you learn to live with multiple myeloma, ask them for support. They will be happy to suggest beneficial programs and services.
PERIPHERAL NEUROPATHY
Peripheral neuropathy. The general term for nerve disorders that impact a particular segment of your nervous system is peripheral neuropathy. Since it can be caused by a variety of disorders, a wide range of symptoms may also be present. The way and cause of peripheral neuropathy can also determine which bodily regions are affected.
PERIPHERAL NEUROPATHY
Damage to the peripheral nerves that link the brain and spinal cord to the rest of the body causes this disorder, which manifests as a range of symptoms include tingling, pain, weakness, and numbness. Along with affecting digestion and urination, it can also affect other parts of the body, such as the hands and feet.
Types
Demyelinating neuropathy: This condition occurs when the axon’s myelin sheath breaks down or fails to develop properly. This has an impact on how signals move through the neuron.
Axonal degeneration: This results in the axon’s degradation and eventual death. The effect is worse the longer the neuron. Your legs and feet, which are located furthest from your spinal cord and depend on connections made by longer axons, are therefore frequently affected by axonal degeneration disorders. The most prevalent pattern of peripheral neuropathy is axonal degeneration.
Symptoms
It can present with a variety of symptoms. A single nerve, an interconnected network of related nerves, or numerous nerves spread throughout your body may be impacted by this illness. Multiple signal types may be implicated, and the symptoms also depend on the sort of nerve signals that are impacted.
The sorts of symptoms (more on these are provided below) are:
Motor.
both pain and sensory.
Autonomic.
Causes
Diabetes type 2. Type 2 diabetes that is left untreated is the most frequent cause of peripheral neuropathy. Excessive blood sugar levels over an extended period of time can harm peripheral nerves. People who have type 2 diabetes may therefore experience a loss of sensation in their lower legs and feet.
addiction to alcohol. Nerve injury can result from excessive alcohol consumption, particularly over extended periods of time. In addition to contributing to vitamin deficiencies that produce peripheral neuropathy, alcohol use disorder is a common cause of peripheral neuropathy.
nutritional and vitamin deficits. When a person is deficient in certain vitamins, nerve injury may result.
Treatment
Medications. Peripheral nervous system issues can be treated with a variety of drugs. These can take many different forms, such as oral pills, injections, skin-sticking patches, slow-release drugs, and more.
Surgery. Reconnecting severed nerves and relieving pain from imprisoned nerves can be accomplished by surgery. In order to prevent damaged or defective nerves from sending signals to the brain and vice versa, it can also cut or delete them.
physical treatment. This might lessen pain symptoms or aid in your recovery from illnesses or injuries. Along with enhancing balance and reducing the risk of falls, it can also assist you in adjusting to changes in your neurological system.
Summary
Peripheral neuropathy may be curable, transient, or both for certain individuals. For others, it’s incurable and permanent. Many of the symptoms or manifestations of peripheral neuropathy can now be treated because of advancements in medical research and technology. Many people can live longer and with fewer limitations or effects from the associated diseases and symptoms if they manage this condition.
PENILE CANCER
Penile cancer. When your penis’s healthy cells alter and proliferate uncontrollably, penile cancer results. The rod-shaped reproductive organ that enables urination and sexual activity is your penis. It consists of the glans, a rod-like region (shaft) that runs from your low abdomen to the tip of your penis. The foreskin is a layer of skin that covers the head if you are not circumcised. Your penis’ head is visible if you have had circumcision.
PENILE CANCER
Cancer can develop anywhere in the penis, but if you are not circumcised, it usually begins on the head or foreskin. Penile cancer, a relatively uncommon cancer of the penis, is frequently a squamous cell carcinoma, originating from the skin cells. Uncircumcision, HPV infection, smoking, and poor hygiene are risk factors. Successful treatment, which may include chemotherapy, radiation, or surgery, depends on early detection.
Types
SCC stands for squamous cell cancer. The epithelium, the outermost layer of your skin, is where this cancer develops. 95% of all penile malignancies are of this type.
Melanoma. Melanocytes, the cells that regulate how dark or light your skin is, are where this type of cancer starts. A more aggressive type of cancer is melanoma.
BCC, or basal cell cancer. The lowermost layer of your epithelium is where the cancer starts. BCC is a type of penile cancer that grows slowly.
Adenocarcinoma. Your glandular cells, which produce perspiration, mucus, and other bodily fluids, are where this cancer begins.
cancer of the urothelium. The urothelium, the tissue lining your bladder, kidneys, and other urinary system organs, is where this cancer develops.
Sarcoma. Muscle or connective tissue is where this kind of cancer first appears.
Signs
Not every cancer results in visible alterations. However, penile cancer typically results in a change in the appearance of your penis. There may be a lump and discoloration of the skin on your penis.
Symptoms of penile cancer include:
A sore or bump that doesn’t hurt and could leak
Flat growths with a blueish-brown appearance
Something that smells bad beneath your foreskin Rash
Skin thickening or color change
little, crusty lumps
inflammation and swelling, particularly in the penis’ head (balanitis)
These symptoms are sometimes brought on by less serious illnesses including allergies and infections. Don’t leave anything to chance, though. To ensure that early-stage cancer is not left untreated, it is preferable to have a medical professional examine it.
Causes
When healthy cells alter and proliferate uncontrollably, cancer results. However, scientists are unsure of the initial reason of that transformation.
Although they haven’t discovered any reasons, researchers have discovered risk factors.
Treatment
Circumcision. Your doctor might remove the tissue if the cancer is limited to your foreskin.
Cryotherapy. Extreme cold is used in this therapy to kill the tumor.
Excision. Your doctor might remove the tumor or cancerous cells from your penis.
Ablation via laser. In order to eliminate the tumor, this treatment uses lasers that produce extremely high temperatures.
creams with medication. You apply this lotion to your penis on a regular basis. Imiciquimod and fluorouracil are common medications.
Mohs surgery. In order to reach the healthy tissue underlying, your healthcare practitioner will remove the malignant skin layer by layer throughout this treatment.
radiation treatment. Before surgery, your doctor might employ energy beams, such as X-rays, to reduce a tumor or kill cancer cells.
Summary
Receiving a diagnosis of penile cancer is a life-altering event that causes a flurry of feelings and questions. Feeling overburdened is normal and acceptable, so it’s crucial to look after yourself during this time. Consult your physician. In addition to discussing possible treatment choices, they can direct you to resources for both emotional and practical support. Rely on your loved ones and medical team. This is not unique to you.
PELVIC ORGAN PROLAPSE
Pelvic organ prolapse. Prolapse of the pelvic organs such as the uterus, bladder,, rectum, and vagina is known as pelvic organ prolapse. The muscles, ligaments, and tissues that support your pelvic organs known as the pelvic floor become insufficiently strong to keep your organs in place. Like a hammock, the pelvic floor provides support for the organs in your pelvis from below. The organs they support may droop into the vagina or move out of position if these supports get too loose. Your pelvic floor may become weaker as you age or after giving birth.
PELVIC ORGAN PROLAPSE
It is a disorder in which one or more organs (the vagina, uterus, bladder, and rectum) sag due to weak pelvic muscles. In more extreme situations, an organ protrudes outside of your body or onto another organ. Treatments to correct the prolapse and alleviate your symptoms may be suggested by your healthcare practitioner.
Types
prolapse of the anterior vaginal wall (bladder drop). Your bladder may slide out of position and protrude into your vagina if the pelvic floor muscles above it are weak. Cystocele is another name for this kind of prolapse. The most prevalent kind of POP is anterior vaginal wall prolapse.
Urethrocele. If you have weak pelvic floor muscles, your urethra may descend. A fallen bladder is frequently followed by a dropped urethra.
prolapse of the posterior vaginal wall (rectocele). Your rectum may protrude onto the rear wall of your vagina due to weak pelvic floor muscles between it and your vagina.
Signs
Feeling as though something is dropping out of your vagina is the most typical symptom. Other signs and symptoms include:
Pressure or fullness in your vagina
Pelvic fullness, pressure, or soreness
Dyspareunia, or pressure or pain during sexual activity
Changes in the way you urinate or defecate
The location of the prolapse determines your symptoms. Your doctor can identify the areas where your pelvic floor is weaker if you tell them about your problems.
Causes
giving delivery vaginally. The most frequent reason for prolapse is this. Your pelvic floor muscles are more likely to deteriorate if you have twins or triplets, have many vaginal deliveries, have a huge baby (fetal macrosomia), or have a vacuum or forceps delivery.
the process of aging. As you age, your muscles become weaker. Declining estrogen is one of the factors. Your body makes less estrogen while you go through menopause. Your pelvic floor’s supporting connective tissues may deteriorate as a result of the deterioration.
weighing more than average. According to studies, those who are overweight or obese have a higher risk of developing POP than those who are within a healthy weight range.
Treatment
pessary vaginal. To keep a drooping organ in place, your healthcare professional can install this detachable silicone device into your vagina.
Kegel exercises for the pelvic floor. These are pelvic floor strengthening exercises. To evaluate the strength of specific muscles and teach you specific exercises to train them, your healthcare physician could recommend that you see a pelvic floor specialist or urogynecologist.
A shortened vagina is the consequence of the obliterative operation known as colpocleisis. It stops any organs from protruding from your body. If you no longer want penetrative sex and are too weak for reconstructive surgery, this is a good alternative.
Reconstructive surgery restores the organs to their normal position and strengthens the weak areas of your pelvic floor.
Summary
Pelvic organ prolapse is not a life-threatening condition, but it doesn’t mean you have to accept it. You may experience symptoms that make it difficult to fully enjoy life and engage in activities you enjoy. Recognize that you are not alone and that women frequently experience pelvic floor problems. If you believe that your pelvic floor is weak, don’t be afraid to discuss it with your doctor.
Plantar Fascia
Peripheral Neuropathy
Penile Cancer
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